Dress Vs Serum Sickness. Antiserum is the liquid part of the blood containing antibodies that is administered to individuals for protection against effects of poison or germs. In late phase T-regs become functionally defficient as DRESS resolves perhaps allowing for the development of autoimmune disease.
The differential should also include drug-induced lupus erythematosus Kawasaki syndrome serum sickness-like reaction hypereosinophilic syndrome drug-induced pseudolymphoma and staphylococcal toxic shock syndrome. How do we differentiate. Serum sickness Serum sickness is the prototypic example of the Gell and Coombs type III.
The reaction requires the presence of the antigen coincident with antibodies directed against the antigen leading to the formation of antigen-antibody or immune complexes.
Consider with arthralgias and diffuse mucositis. The differential should also include drug-induced lupus erythematosus Kawasaki syndrome serum sickness-like reaction hypereosinophilic syndrome drug-induced pseudolymphoma and staphylococcal toxic shock syndrome. 682014 During the acute phase of DRESS regulatory Tcells T-regs are expanded and functionally more robust. Serum sickness is a condition characterized by abnormal behavior of the immune system in response to certain drugs containing protein of other species or antiserum.